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副教授

袁焕祥

  

博士,副教授,硕士生导师

通讯地址:北京市海淀区阜成路11号

联系方式:yuanhuanxiang@btbu.edu.cn

个人简历:

2005年-2009年,于中国农业大学化学专业毕业,获理学学士学位。

2009年-2011年,于中国科学院有机化学专业毕业,获理学硕士学位。

2011年-2014年,于中国科学院有机化学专业毕业,获理学博士学位。

2014年至今,于北京工商大学化学与材料工程学院化学系授课,任系副主任、副教授。

主要研究领域:

1.共轭聚合物的设计合成及其在抗菌、靶向抗癌方面的应用;

2.有机荧光纳米材料的制备及其在生物医药领域的应用

主讲课程:

本科:《有机化学(双语)》《化学科技文献选读》《化学专业英语》

研究生:《化学工艺学》

主要科研项目:

(一)主持国家自然科学基金青年项目(2016-2018)

(二)主持北京市优秀人才计划项目(2016-2018)

(三)主持国家分子实验室开放项目(2017-2019)

(四)主持北京市教委一般项目(2019-2020)

(五)主持北京市属高校教师队伍建设优秀青年人才培育计划项目(2023-2025)

(六)主持北京工商大学青年启动基金(2015-2016)

近年发表的主要科研论文:

1. Huanxiang Yuan(袁焕祥), Zelin Li, Qi Zhao, Shaochuan Jia, Ting Wang, Li Xu*, Haitao Yuan*, Shengliang Li*. Molecular Evolution of Acceptor-Donor-Acceptor-type Conjugated Oligomer Nanoparticles for Efficient Photothermal Antimicrobial Therapy. Adv. Funct. Mater. 2023, 33, 2213209. (Q1,影响因子:19.924)

2. Huanxiang Yuan(袁焕祥), Shaochuan Jia, Zelin Li, Haitao Yuan. Construction of layer-by-layer self-assembly coatings based on hemicyanine derivative for photodynamic antimicrobial application. Mater. Lett. 2023, 335, 133770. (Q2,影响因子:3.574)

3. Huanxiang Yuan(袁焕祥), Zelin Li, Xiaoyu Wang, Ruilian Qi*. Photodynamic Antimicrobial Therapy Based on Conjugated Polymers. Polymers 2022, 14, 3657. (Q1,影响因子:4.967)

4. Huanxiang Yuan(袁焕祥), Shaochuan Jia, Zelin Li, Jian Liu, Xiaoyu Wang, Ruilian Qi*. Regulation of Antimicrobial Effect of Hemicyanine-Based Photosensitizer via Supramolecular Assembly. Nanomaterials 2022, 12, 2905. (Q1,影响因子:5.719)

5. Shaochuan Jia, Zelin Li, Jinping Shao, Huanxiang Yuan*(袁焕祥), Li Li, Li Xu*. Acceptor Regulation of Acceptor–Donor–Acceptor Type Conjugated Oligomer for Photothermal Combating of Resistant Bacteria. ACS Appl. Polym. Mater. 2022, 4, 5275-5280. (Q1,影响因子:4.855)

6. Shaochuan Jia, Huanxiang Yuan*(袁焕祥), Rong Hu*. Design and Structural Regulation of AIE photosensitizers for imaging-guided photodynamic anti-tumor application. Biomater. Sci., 2022, 10, 4443-4457. (Q1,影响因子:7.59)

7. Zelin Li, Fan Ni, Shaochuan Jia, Li-Hua Gao, Huanxiang Yuan*(袁焕祥), Ke-Zhi Wang*. Bipolar Hemicyanine-Based Photodynamic Modulation of Type I Pathway for Efficient Sterilization and Real-Time Monitoring. ACS Appl. Bio Mater., 2022, 5, 2549-2555.

8. Hualei Xu, ZiyanWu, DanZhao, Haiyan Liang*, Huanxiang Yuan (袁焕祥), ChangtaoWang*. Preparation and characterization of electrospun nanofibers-based facial mask containing hyaluronic acid as a moisturizing component and huangshui polysaccharide as an antioxidant component. Int. J. Biol. Macromol., 2022, 214, 212-219. (Q1,影响因子:8.025)

9. Zelin Li, Li Xu, Huanxiang Yuan*(袁焕祥), and Pengbo Zhang*. Fluorescence Sensor Array Based on Aggregation-Induced Emission Luminogens for Pathogen Discrimination. Analyst, 2022, 147, 2930-2935. (Q1,影响因子:5.227)

10. Zelin Li, Wen Lu, Shaochuan Jia, and Huanxiang Yuan*(袁焕祥). Backbone-Regulated Cationic Conjugated Polymers for Combating and Monitoring Pathogenic Bacteria. ACS Appl. Polym. Mater., 2022, 4, 29-35. (Q1,影响因子:4.855)

11. Ruilian Qi, Jian Liu, Huanxiang Yuan*(袁焕祥) and Yu Yu*. Sulfur-Doped BiOCl with Enhanced Light Absorption and Photocatalytic Water Oxidation Activity. Nanomaterials, 2021, 11, 2221. (Q1,影响因子:5.719)

12. Huanxiang Yuan*(袁焕祥), Zelin Li, Haotian Bai, Chuang Yao, Shaochuan Jia, Ruilian Qi, Li Li, and Cui-Hua Zhao. Aggregation-induced emission nanoparticles with NIR and photosensitizing characteristics for resistant bacteria elimination and real-time tracking. Mater. Chem. Front., 2021, 5, 6611-6617. Q1,影响因子:8.683)

13. Yuchao Liang, Zelin Li, Huanxiang Yuan*(袁焕祥), Lei Wang*, and Li-Hua Gao*. Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy. Sci. Rep., 2021, 11, 4449. Q1,影响因子:4.996)

14. Zelin Li, Haotian Bai, Shaochuan Jia, Huanxiang Yuan*(袁焕祥), Li-Hua Gao, and Haiyan Liang. Design of functional polymer nanomaterials for antimicrobial therapy and combatting resistance. Mater. Chem. Front., 2021, 5, 1236. Q1,影响因子:8.683)

15. Zelin Li, Wen Lu, Shaochuan Jia, Huanxiang Yuan*(袁焕祥), and Li-Hua Gao. Design and Application of Conjugated Polymer Nanomaterials for Detection and Inactivation of Pathogenic Microbes. ACS Appl. Bio Mater., 2021, 4, 370−386.

16. Yuchao Liang, Hongjuan Zhang, Huanxiang Yuan*(袁焕祥), Wen Lu, Zelin Li, Lei Wang, Li-Hua Gao. Conjugated polymer and triphenylamine derivative codoped nanoparticles for photothermal and photodynamic antimicrobial therapy. ACS Appl. Bio Mater., 2020, 3, 3494-3499.

17. Hongjuan Zhang, Yuchao Liang, Hao Zhao, Ruilian Qi, Zhuo Chen, Huanxiang Yuan*(袁焕祥), Haiyan Liang*, and Lei Wang. Dual-mode antibacterial conjugated polymer nanoparticles for photothermal and photodynamic therapy. Macromol. Biosci., 2020, 20, 1900301. Q1,影响因子:5.859)

18. Huijiang Xiang, Pingli Dong, Lei Pi, Zhijie Wang, Tingting Zhang, Siyang Zhang, Chichong Lu, Yao Pan, Huanxiang Yuan(袁焕祥), and Haiyan Liang. One-pot synthesis of water-soluble and biocompatible superparamagnetic gadolinium-doped iron oxide nanoclusters. J. Mater. Chem. B, 2020, 8, 1432-1444. Q1,影响因子:7.571)

19. Shanshan Liu, Huanxiang Yuan(袁焕祥), Haotian Bai, Pengbo Zhang, Fengting Lv, Libing Liu, Zhihui, Dai, Jianchun Bao, and Shu Wang, Electrochemiluminescence for electric-driven antibacterial therapeutics. J. Am. Chem. Soc., 2018, 140, 2284-2291. Q1,影响因子:16.383)

20. Zhuo Chen, Huanxiang Yuan*(袁焕祥), Haiyan Liang, Chichong Lu, and Xiaolan Liu, Synthesis of a cationic poly(p-phenylenevinylene) derivative for lysosome-specific and long-term imaging. Chinese Chem. Lett., 2018, 29, 339-341. Q1,影响因子:8.455)

21. Zhuo Chen, Huanxiang Yuan*(袁焕祥), and Haiyan Liang, Synthesis of multifunctional cationic poly(p-phenylenevinylene) for selectively killing bacteria and lysosome-specific imaging. ACS Appl. Mater. Interfaces, 2017, 9, 9260-9264. Q1,影响因子:10.383)

22. Huanxiang Yuan*(袁焕祥), Lifang Wang, Shuhong Li, Haiyan Liang, Chichong Lu, Yibo Wang, Cui-Hua Zhao*, The preparation of organoboron-based stilbene nanoparticles for cell imaging. J. Mater. Chem. B, 2016, 4, 5515-5518. Q1,影响因子:7.571)

23. Huanxiang Yuan(袁焕祥), Libing Liu, Fengting Lv, Shu Wang. A glucose-powered antimicrobial system using organic–inorganic assembled network materials. Chem. Commun. 2015, 51, 722-724. Q1,影响因子:6.065)

24. Huanxiang Yuan(袁焕祥), Bing Wang, Fengting Lv, Libing Liu, Shu Wang. Conjugated polymer-based energy transfer systems for antimicrobial and anticancer applications. Adv. Mater. 2014, 26, 6978-6982. Q1,影响因子:32.086)

25. Huanxiang Yuan(袁焕祥), Libing Liu, Fengting Lv, Shu Wang. Cationic conjugated polymers for discrimination of microbial pathogens. Adv. Mater. 2014, 26, 4333-4338. Q1,影响因子:32.086)

26. Huanxiang Yuan(袁焕祥), Libing Liu, Fengting Lv, Shu Wang. Bioluminescence as a light source for photosynthesis. Chem. Commun. 2013, 49, 10685-10687. Q1,影响因子:6.065)

27. Huanxiang Yuan(袁焕祥), Hui Chong, Bing Wang, Chunlei Zhu, Libing Liu, Qiong Yang, Fengting Lv, Shu Wang. Chemcial molecule-induced light-activated system for anticancer and antifungal activities. J. Am. Chem. Soc. 2012, 134, 13184-13187. Q1,影响因子:16.383)

28. Chichong Lu, Pingli Dong, Lei Pi, Zhijie Wang, Huanxiang Yuan(袁焕祥), Haiyan Liang, Dongge Ma, and Kyu Yun Chai, Hydroxyl-PEG-phosphonic acid-stabilized superparamagnetic manganese oxide-doped iron oxide nanoparticles with synergistic effects for dual-mode MR imaging. Langmuir, 2019, 35, 9474-9482. Q2,影响因子:4.331)

29. Jianmei Ma, Hao Wang, Chenglin Wang, Huanxiang Yuan(袁焕祥), Dongsheng Bai, Kyu Yun Chai, Chichong Lu, Synthesis, antioxidant and antimelanogenic activities of PEGylated alpha-tocopheryl lipoate conjugates. J. Dermatol. Sci., 2017, 86, 73-75. Q1,影响因子:4.563)

30. Chichong Lu, Hao Wang, Jianmei Ma, Huanxiang Yuan*(袁焕祥), Haiyan Liang, Lingrong Wu, Kyu Yun Chai, and Shuhong Li. Facile synthesis of superparamagnetic magnetite nanoflowers and their applications in cellular imaging. RSC Advances, 2016, 6, 42649-42655. (影响因子:4.036)

31. Shengliang Li, Huanxiang Yuan(袁焕祥), Hui Chen, Xiaoyu Wang, Pengbo Zhang, Fengting Lv, Libing Liu, and Shu Wang, Cationic poly(p-phenylene vinylene) materials as a multifunctional platform for light-enhanced sirna delivery. Chem-Asian J., 2016, 11, 2686-2689. Q2,影响因子:4.839)

32. Haotian Bai, Huanxiang Yuan(袁焕祥), Chenyao Nie, Bing Wang, Fengting Lv, Libing Liu, Shu Wang. Supramolecular antibiotic switch for antibacterial regulation. Angew. Chem. Int. Ed. 2015, 54, 13208-13213. Q1,影响因子:16.823)

33. Han Sun, Bohan Yin, Hongli Ma, Huanxiang Yuan(袁焕祥), Bin Fu, and Libing Liu, Synthesis of a novel quinoline skeleton introduced cationic polyfluorene derivative for multimodal antimicrobial application. ACS Appl. Mater. Interfaces, 2015, 7, 25390-25395. Q1,影响因子:10.383)

34. Fen Wu, Juan Jin, Liying Wang, Pengfei Sun, Huanxiang Yuan(袁焕祥), Zhongqiang Yang, Guosong Chen, Qing-Hua Fan, and Dongsheng Liu. Functionalization of DNA-dendron supramolecular fibers and application in regulation of escherichia coli association. ACS Appl. Mater. Interfaces, 2015, 7, 7351-7356. Q1,影响因子:10.383)

35. Bing Wang, Huanxiang Yuan(袁焕祥), Zhang Liu, Chenyao Nie, Libing Liu, Fengting Lv, Yilin Wang, Shu Wang, Cationic oligo(p-phenylene vinylene) materials for combatting drug resistance of cancer cells by light manipulation, Adv. Mater. 2014, 26, 5986-5990. Q1,影响因子:32.086)

36. Rong Hu, Huanxiang Yuan(袁焕祥), Bing Wang, Libing Liu, Fengting Lv, and Shu Wang, DNA hydrogel by multicomponent assembly for encapsulation and killing of cells, ACS Appl. Mater. Interfaces 2014, 6, 11823-11828. Q1,影响因子:10.383)

37. Bing Wang, Jinzhao Song, Huanxiang Yuan(袁焕祥), Chenyao Nie, Fengting Lv, Libing Liu, Shu Wang. Multicellular assembly and light regulation of cell-cell communication by conjugated polymer materials. Adv. Mater. 2014, 26, 2371-2375. Q1,影响因子:32.086)

38. Meng Li, Chenyao Nie, Liheng Feng, Huanxiang Yuan(袁焕祥), Libing Liu, Fengting Lv, Shu Wang. Conjugated polymer nanoparticles for cell membrane imaging. Chem-Asian J. 2014, 9, 3121-3124. Q2,影响因子:4.839)

39. Liheng Feng, Chunlei Zhu, Huanxiang Yuan(袁焕祥), Libing Liu, Fengting Lv, Shu Wang. Conjugated polymer nanoparticles: preparation, properties, functionalization and biological applications. Chem. Soc. Rev. 2013, 42, 6620-6633. Q1,影响因子:60.615)

40. Ali Cao, Yanli Tang, Yue Liu, Huanxiang Yuan(袁焕祥), Libing Liu. A strategy for antimicrobial regulation based on fluorescent conjugated oligomer-DNA hybrid hydrogels. Chem. Commun. 2013, 49, 5574-5576. Q1,影响因子:6.065)

41. Kai Liu, Yiliu Liu, Yuxing Yao, Huanxiang Yuan(袁焕祥), Shu Wang, Zhiqiang Wang, Xi Zhang. Supramolecular photosensitizers with enhanced antibacterial efficiency. Angew. Chem. Int. Ed. 2013, 52, 8285-8289. Q1,影响因子:16.823)

42. Gaomai Yang, Huanxiang Yuan(袁焕祥), Chunlei Zhu, Libing Liu, Qiong Yang, Fenting Lv, Shu Wang. New conjugated polymers for photo-induced unwinding of DNA supercoiling and gene regulation. ACS Appl. Mater. Interfaces 2012, 4, 2334-2337. Q1,影响因子:10.383)

43. Bing Wang, Huanxiang Yuan(袁焕祥), Chunlei Zhu, Qiong Yang, Fengting Lv, Libing Liu, Shu Wang. Polymer-drug conjugates for intracellar molecule-targeted photoinduced inactivation of protein and growth inhibition of cancer cells. Sci. Rep. 2012, 2, 766. Q1,影响因子:4.996)

已授权或申请发明专利:

1. 王树,袁焕祥,刘礼兵,一种光动力治疗药物、药物组合物及其制备方法,中国专利,专利号:ZL201210234471.X

2. 袁焕祥,张红娟,一种共轭聚合物和聚集诱导发光小分子共掺的纳米粒子及其制备方法和应用,中国专利,专利号:ZL202010069750.X

3. 袁焕祥,张红娟,双模式共轭聚合物纳米颗粒、其制备方法及其应用,中国专利,专利号:ZL201910613896.3

4. 袁焕祥,陈卓,一种有机共轭小分子纳米粒子及其制备方法和应用,中国专利,专利号: ZL202010076208.7

获奖情况:

1. 2022年6月,获评优秀硕士论文指导教师;

2. 2022年2月,获评2021年度北京工商大学优秀研究生导师;

3. 2016年11月,获第八届北京工商大学青年教师教学基本功大赛二等奖;

4. 2015年6月,获第五届北京工商大学青年学术演讲比赛二等奖;

5. 2015年7月,获中国科学院优秀博士论文;

6. 2014年7月,获中国科学院院长特别奖。